Find the EV needle in the haystack with Leprechaun

Live30 webinars are thirty-minute presentations designed to update you on the latest innovations, applications, and data in a fast yet interactive format.

The Problem: 

Finding a needle in a haystack can be a nightmare or no problem at all if you’ve got the right tool for the job – characterizing extracellular vesicle (EV) or exosome samples can be the exact same way. Even in highly purified cell culture samples, interference can come from lipoproteins, cell debris or protein aggregates getting in the way of sizing, quantification, or spotting the frequency of your target particles. The situation gets tougher in complex biofluids, with limited sample volumes, or when tracking down rare EV subpopulations.  

The Solution: 

Leprechaun grabs all the EVs it can with a new, pooled pan-tetraspanin capture surface that enables analysis on particle size, total EV concentration, and subpopulation frequency. Check out any phenotype with out-of-the-box or customizable fluorescent secondary antibodies in an approach that needs just a few microliters of sample. With particle-by-particle surface analysis and size analysis down to 35 nm, Leprechaun is ready to spot your rare EV in any population of lookalike particles.  

The Proof: 

In this webinar we’ll take a look at how Leprechaun runs any EV sample through single particle interferometry for sizing and immunofluorescence for surface marker detection. We’ll discuss new analysis modes that use a pooled tetraspanin capture approach to quantify total EV populations to help understand the count and frequency for unique EV subpopulations and gives a complete size breakdown of everything it sees.