Protein stability insights you can only get on Uncle
The Problem: Complex protein stability problems demand insightful answers. When working with many different proteins, you want one flexible platform that packs the tools to handle both the usual and the exotic candidates: those with unusual compositions that don’t show fluorescence, those that require buffers that quench fluorescence, those that carry a payload, and those associated with membranes. This platform needs to deliver enough data from any given sample to get you the full story.
The Solution: Uncle combines three technologies to get you all the data you need in one shot. Uncle’s full spectrum fluorescence gives visibility into usual and unusual ways your protein is unfolding and opens the door to solving even harder problems with dyes like SYPRO Orange, CPM, or SYBR Gold. Uncle’s SLS gives you access to simultaneous aggregation data even at very low or very high concentrations – or you can check out formulations in a flash with light scattering data on protein self-interaction. On top of all that, Uncle’s dynamic light scattering checks size and delivers confidence that samples weren’t aggregated to start with.
The Proof: Join our seminar to learn about the protein problems that only Uncle’s unique toolset can answer – and where other methods fall short. Grabbing all that data on Uncle just can’t be substituted with something else.
